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4.
Arch. Soc. Esp. Oftalmol ; 94(12): 602-604, dic. 2019. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-190012

RESUMO

La toxoplasmosis ocular es una enfermedad que puede tener graves consecuencias visuales. El objetivo es presentar un caso clínico de toxoplasmosis ocular bilateral severa en una paciente alérgica a sulfamidas en el que la reactivación monolateral de la enfermedad responde de forma favorable ante el tratamiento con clindamicina intravítrea y corticoterapia oral. Se muestra como la administración de clindamicina mediante inyecciones intravítreas semanales supone una alternativa terapéutica segura en aquellos casos de toxoplasmosis ocular severa y/o en los que existe contraindicación para el tratamiento clásico. La clindamicina intravítrea es una alternativa terapéutica segura con resultados clínicos favorables


Ocular toxoplasmosis is a disease than have severe consequences on the eyesight. The aim of this study article is to present a bilateral ocular toxoplasmosis in a sulfamide allergic patient with unilateral activation and her favourable progression with intravitreal Clindamycin and oral steroids treatment. Weekly intravitreal Clindamycin treatment is shown to be a suitable therapeutic alternative in cases of severe ocular toxoplasmosis and/or in patients with a contraindication to classical treatment. Intravitreal Clindamycin treatment is a safe alternative with favourable clinical results


Assuntos
Humanos , Feminino , Adulto , Antibacterianos/administração & dosagem , Clindamicina/administração & dosagem , Toxoplasmose Ocular/tratamento farmacológico , Angiofluoresceinografia , Injeções Intravítreas , Tomografia de Coerência Óptica , Toxoplasmose Ocular/diagnóstico por imagem
5.
Arch Soc Esp Oftalmol (Engl Ed) ; 94(12): 602-604, 2019 Dec.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-31607401

RESUMO

Ocular toxoplasmosis is a disease than have severe consequences on the eyesight. The aim of this study article is to present a bilateral ocular toxoplasmosis in a sulfamide allergic patient with unilateral activation and her favourable progression with intravitreal Clindamycin and oral steroids treatment. Weekly intravitreal Clindamycin treatment is shown to be a suitable therapeutic alternative in cases of severe ocular toxoplasmosis and/or in patients with a contraindication to classical treatment. Intravitreal Clindamycin treatment is a safe alternative with favourable clinical results.


Assuntos
Antibacterianos/administração & dosagem , Clindamicina/administração & dosagem , Toxoplasmose Ocular/tratamento farmacológico , Adulto , Feminino , Angiofluoresceinografia , Humanos , Injeções Intravítreas , Tomografia de Coerência Óptica , Toxoplasmose Ocular/diagnóstico por imagem
10.
Arch Soc Esp Oftalmol ; 83(4): 267-71, 2008 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-18373301

RESUMO

CASE REPORT: Ocular examinations and optical coherence tomography (OCT) were performed in three patients with retinal phototoxicity lesions. Fluorescein angiography depicted a window defect. OCT exhibited hyporeflectivity at the outer foveal retina and fragmentation of the inner reflective layers, corresponding to the junction between the inner and outer photoreceptor segments. DISCUSSION: Retinal damage after light exposure has a rapid onset and shows different patterns in OCT examination. OCT findings suggest that decreased visual acuity may be associated with full-thickness photoreceptors and retinal pigment epithelium (RPE) involvement. OCT is a useful tool for objective assessment of retinal pathology in phototoxicity cases where fundus changes may be minimal or absent.


Assuntos
Luz/efeitos adversos , Macula Lutea , Doenças Retinianas/diagnóstico , Doenças Retinianas/etiologia , Tomografia de Coerência Óptica , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Retina/lesões , Retina/patologia
11.
Arch. Soc. Esp. Oftalmol ; 83(4): 267-272, abr. 2008. ilus
Artigo em Es | IBECS | ID: ibc-63092

RESUMO

Caso clínico: Se realiza una exploración ocular y tomografía de coherencia óptica (OCT) en tres pacientes con lesiones fototóxicas retinianas. Las angiografías fluoresceínicas muestran un defecto ventana. La OCT muestra hiporreflectividad en la porción externa de la fóvea y fragmentación de las capas más internas entre la porción interna de los fotorreceptores y los segmentos externos. Discusión: Las lesiones retinianas tras exposición a la luz aparecen precozmente mostrando diferentes patrones en la OCT. La OCT sugiere que la disminución de visión asocia una lesión de fotorreceptores y epitelio pigmentario retiniano (EPR). La OCT es útil para objetivar la retinopatía fototóxica donde los cambios oftalmoscópicos pueden estar ausentes o ser mínimos


Case report: Ocular examinations and optical coherence tomography (OCT) were performed in three patients with retinal phototoxicity lesions. Fluorescein angiography depicted a window defect. OCT exhibited hyporeflectivity at the outer foveal retina and fragmentation of the inner reflective layers, corresponding to the junction between the inner and outer photoreceptor segments. Discussion: Retinal damage after light exposure has a rapid onset and shows different patterns in OCT examination. OCT findings suggest that decreased visual acuity may be associated with full-thickness photoreceptors and retinal pigment epithelium (RPE) involvement. OCT is a useful tool for objective assessment of retinal pathology in phototoxicity cases where fundus changes may be minimal or absent (Arch Soc Esp Oftalmol 2008; 83: 267-272)


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Dermatite Fototóxica/diagnóstico , Tomografia de Coerência Óptica/métodos , Doenças Retinianas/etiologia , Luz Solar/efeitos adversos
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